Medical Imaging Mutifractal Analysis in Prediction of Efficiency of Cancer Therapy

Based on pressing need for predictive performance improvement, we explored the value of pretherapy tumour histology image analysis to predict chemotherapy response. It was shown that multifractal analysis of breast tumour tissue prior to chemotherapy indeed has the capacity to distinguish between histological images of the different chemotherapy responder groups with accuracies of 91.4% for pPR, 82.9% for pCR and 82.1% for PD/SD.